![NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]](https://i.ytimg.com/vi/IgLQ5p3myIA/hqdefault.jpg "NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]")
NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]
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![NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]](https://bloximages.newyork1.vip.townnews.com/dothaneagle.com/content/tncms/assets/v3/editorial/d/94/d947861b-98c2-5434-8dcb-dd5c03feb358/64ea7301717da.image.jpg?crop=1763%2C926%2C0%2C124&resize=1200%2C630&order=crop%2Cresize "NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]")
The 49ers' heavy investment in QB Trey Lance backfires
![NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]](https://cdn.vox-cdn.com/thumbor/wmBGZj26ngsBuu7kxercjO32ZhI=/1400x1400/filters:format(jpeg)/cdn.vox-cdn.com/uploads/chorus_asset/file/23972196/1418077145.jpg "NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]")
49ers finish the preseason with a sloppy 17-0 loss to Texans
![NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]](https://www.kolotv.com/resizer/7YaagTdD2qepUaiix_W0hR-CFVw=/arc-photo-gray/arc3-prod/public/JQ3CMOE5NRJH3AFPC2NHXRFUME.jpg "NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]")
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![NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]](https://sportshub.cbsistatic.com/i/r/2022/08/24/bbbf2e03-6f32-49df-9d53-71e683ba5e1b/thumbnail/1200x675/e8ad25f655a9afe32485a0dab3fbd97d/elijah-mitchell-getty-images-49ers.jpg "NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]")
49ers vs. Texans odds, spread, line: 2022 NFL preseason Week 3
![NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]](https://bloximages.newyork1.vip.townnews.com/uniondemocrat.com/content/tncms/assets/v3/editorial/2/f4/2f4f7df6-4212-11ee-8333-5b705ce9d2e1/64e69fc6c67be.image.jpg?resize=400%2C289 "NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]")
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![NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]](https://a57.foxsports.com/statics.foxsports.com/www.foxsports.com/content/uploads/2022/01/1280/1280/1.24.22_NFC-Championship-Lines-Picks-for-49ers-Rams_16x9.jpg?ve=1&tl=1 "NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]")
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![NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]](https://media.bleacherreport.com/image/upload/c_fill,g_faces,w_1600,h_1600,q_95/v1689715445/gg9xhrkse8widjthe8th.jpg "NFL Preseason: 49ers vs Texans Preview [Pick + O/U Wins for each team]")
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49ers vs. Texans odds, spread, line: 2022 NFL preseason Week 3
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